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KMID : 0370219980420030307
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Yakhak Hoeji
1998 Volume.42 No. 3 p.307 ~ p.311
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The Inhibitory Effects of Taraxaci Herba against Cadmium Induced Cytotoxicity
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한두석/Han DS
이기남/이종섭/백승화/Lee KN/Lee JS/Baek SH
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Abstract
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This study was carried out to evaluate antitoxic effects Taraxaci Herba extract against Cadium by calorimetric methods. The antitoxic activity of Taraxaci Herba ex tract in NIH 3T3 fibroblasts was evaluated by MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-phenyl-2H-tetrazoliumbromide), NR (Neutral red) and SRB (Sulforhodamine B protein) assay. The light microscopic study was carried out to observe morphological changes of the treated cells. These results were obtained as follows; The concentration of 10-2mg/ml of Taraxaci Herba extract was shown significant antitoxic activity. The number of NIH 3T3 fibroblasts were antitoxic and tend to regenerate. These results suggest that Taraxaci Herba extract retains a potential antitoxic activity.
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